Best Testosterone Supplements That Work

Most testosterone supplements contain core natural ingredients such as Tongkat Ali, Ashwagandha, Maca or Panax Ginseng, Magnesium, Zinc and other ingredients.

And each testosterone supplement brand has its own unique formula.

But which is the best testosterone supplement that works?

This article shares more insights into testosterone supplements, a review of the best testosterone supplements and which is the best natural testosterone booster that you should buy.


Testosterone supplements are used by men and women to supplement the declining gap in testosterone levels as they age. 

Natural testosterone supplements contains plant-based ingredients, or a mix of other vitamins or minerals that boost total and free (usable) testosterone in our body.

You may find testosterone supplements effective as a sustainable long term solution if you exhibit low testosterone symptoms such as:

  • Low sex drive
  • Erectile dysfunction
  • Low stamina
  • Decreased in energy
  • Mild stress, depression or lack of focus

"When testosterone drop below the lower limit, they can start experiencing symptoms like diminished sex drive, erectile dysfunction, subfertility, low stamina, muscle atrophy, decreased energy and lower mood."

According to research expert Dr. Annie George (Head Scientist of Biotropics), natural testosterone supplements such as Tongkat Ali work best as it has been clinically tested on men between 25 to 75.

She added, “Natural testosterone supplements are considered a relatively safe option to TRT or HRT due to fewer long-term side effects”.

Key ingredients behind testosterone supplements

Some of the best natural testosterone supplement contains Tongkat Ali (200 mg to 400 mg), Ashwagandha (600 mg or more) or a mix of Fadogia-Tongkat Ali (600 mg to 1,000 mg).

Core Ingredients

Active ingredients found in most testosterone supplements.

  • Tongkat Ali
  • Ashwagandha
  • Panax Ginseng
  • Fadogia Agrestis
  • Horny Goat Weed
  • Tribulus Terrestris
Non-Core Ingredients

Supporting ingredients found in testosterone supplements that amplify or produce testosterone-like effects.

  • Green Tea
  • Vitamin D
  • D-Aspartic acid
  • Fenugreek
  • Pomegranate
  • Zinc
  • Vitamin B6
  • Black pepper
  • Garlic extract
  • Vitamin B5
  • Magnesium
  • Melatonin
  • Maca
  • Horny Goat Weed
  • Calcium
  • Boron
  • Bioprene

Not all ingredients or herbs are proven to boost testosterone. Some lack clinical tests or scientific evidence. Some testosterone boosters contain ingredients that may produce negative drug interactions, thus further increasing toxic risks or liver damage.

Please consult your nearest doctor before consuming any testosterone boosters.

Does Testosterone Supplement Work?

Most testosterone supplements do not work as intended but a handful of natural testosterone supplements such as Tongkat Ali have been clinically tested to boost total and free testosterone.

According to a research study on 50 testosterone supplements sold in the US, only 24.8% contain ingredients that are verified to boost testosterone and Tongkat Ali tops the list.

Natural testosterone supplements containing Maca, Horny Goat Weed, Fadogia and Ashwagandha may produce marginal testosterone improvements, even at high doses.

Only 24.8% of T-boosters in the US had sufficient data to support its health claims

With more than 500 testosterone boosters supplements on AmazonTongkat Ali and Panax Ginseng are the only two herbs that are time-tested to boost testosterone backed by sufficient human studies over the last two decades. 

Which is the best natural testosterone booster?

According to scientists from the University of Southern California, Tongkat Ali emerged as the top testosterone booster which is backed by sufficient human studies and clinical trials in the two decades.

A research study on the top 50 testosterone supplements (T-booster) by the Institute of Urology from the University of Southern California showed Tongkat Ali, Panax Ginseng and Horny Goat Weed have sufficient evidence to back its testosterone boosting capabilities.

T-Booster Ingredients

Does it increase testosterone?

Tongkat Ali


Panax Ginseng


Horny Goat Weed




D-Aspartic Acid

Tribulus Terrestris

Black pepper


Vitamin B5

Green Tea

Vitamin D

Vitamin B6








Gingko Biloba


Source: Testosterone Boosting Supplements Composition and Claims Are not Supported by the Academic Literature, Chase G et. al. (The World Journal of Men’s Health, Jan 2019)


✅✅✅✅✅ Substantial evidence with significant results

✅✅✅✅ Sufficient evidence with moderate results

✅✅ Moderate evidence with mixed results

✅ Lack of evidence with mixed results

❌ No evidence and it may not work

Which natural supplement works best for testosterone?

Tongkat Ali and Panax Ginseng are both tested on humans to deliver the most testosterone gains. The best natural testosterone supplements contain pure Tongkat Ali root extract or Panax Ginseng extract.

Does Fadogia boost testosterone?

There is limited study on Fadogia Agrestis to prove its effectiveness in increasing testosterone. Increasing Fadogia’s dosage will not boost testosterone but will cause more damage to your liver and kidneys.

Which type of supplement will not work on testosterone?

A study by the University of Southern California in 2019 shows that testosterone supplements containing D-aspartic acid, Black Pepper, Tribulus Terrestris, Zinc, Magnesium, Turkestesterone, and Fadogia Agrestis do not have sufficient clinical studies, clinical tests, or research studies to prove their effect on testosterone.

"Tongkat Ali is the one and only active ingredient that is clinically proven and tested to improve testosterone and men’s health."

Best Testosterone Supplements For Men

Here are the best-selling testosterone supplements in the US, UK, Australia and Europe based on consumer feedback and market research conducted by Berkshire Media.

Best Proven Testosterone Supplement: Single Ingredient

Popular Testosterone Supplement: Multi-Ingredients


AKARALI is the best natural testosterone supplement for men above 40 and 50s due to its clinically tested US-patented proprietary extract, with more than 26 clinical trials since 2003.

Available on Amazon and in other 30 countries, AKARALI’s MIT-formulated Physta® Tongkat Ali is clinically tested to boost testosterone based on clinical studies and works well on adults between 20 to 70 years old.

Most customer reviews on AKARALI reported positive results on testosterone effects such as libido and strength after 48 hours. Maximum peak benefit can be felt after four to twelve weeks.

If you are into single-ingredient formulations, AKARALI Tongkat Ali remains the best herbal supplement for testosterone in 2023.

Key Ingredients 
  • Tongkat Ali standardized root extract 200mg per capsule


  • Scientifically proven testosterone gains between 40% up to 681%
  • Clinically tested to increase DHEA
  • Clinically tested on both men and women
  • Scientifically proven with 26 clinical tests
  • 12 proven health benefits.
  • Proprietary highly potent Tongkat Ali extract
  • Can be consumed in small doses
  • Suitable for both men and women
  • No side effects
  • 140 million doses produced and sold worldwide
  • Standardized extract protocol
  • Highly dependent on daily dosage to realize optimal gains.
  • Must be taken with regular exercises


TestoPrime is a high-performing testosterone booster with a mix formulation of Panax Ginseng, Zinc, Ashwagandha, Black Pepper, Green Tea, Garlic extract. It is sold worldwide and popular amongst heavy lifters and bodybuilders.

Its all-in-one formulation consists high dose of active ingredients that are formulated to deliver testosterone gains which may overwhelm those who are less active.

TestoPrime’s proprietary formulation is not clinically tested and may not be suitable for less active older men or general use.

However, if you are a serious bodybuilder or sports amateur who is seeking that extra boost from your training, TestoPrime is worth a try.

Key Ingredients (4 capsules per servings):
  • Green Tea Extract 4000mg
  • D-Aspartic acid 2000mg
  • Pomegranate Extract 4000mg
  • Panax Ginseng 8000mg
  • Garlic extract 1200mg
  • Vitamin D
  • Fenugreek 800mg
  • Zinc 40mg
  • Ashwagandha Extract 668mg
  • Vitamin B6 5.6mg
  • Black pepper extract
  • Vitamin B5 8mg
  • 90% of the ingredients are from natural herbs
  • Multi nutrients from multiple ingredients
  • Testosterone increase claim between 40 – 60%
  • Formulation not clinically tested on humans
  • Not clinically tested for efficacy
  • May cause jittery or insomnia
  • Must be consumed in high dosages (4 capsules for each serving) to realize health gains
  • Non-standardized extract

Prime Male

Prime Male is an ideal testosterone stack with its all-in-one ingredient in a single capsule approach.

Prime Male is a popular testosterone supplement in the UK and the US, which is actively promoted by affiliates and social influencers. It contains a mix of natural ingredients and vitamins, making it less organic than TestoPrime’s formulation.

Prime Male claims its proprietary formulation is 100% natural and the use of Ashwagandha and Panax Ginseng extract may produce a a significant testosterone boost.

However, many customers reported the side effects of diarrhea as reported in customer reviews. And users are cautioned on the severe side effects of drugs interaction from high doses of Ashwagandha, Panax Ginseng and Magnesium.

Key Ingredients:
  • Vitamin D3 (as Cholecalciferol)
  • Vitamin K2
  • Vitamin B6
  • Magnesium
  • Zinc
  • D-Aspartic Acid
  • Panax Ginseng
  • Luteolin
  • Ashwagandha
  • Nettle Root
  • Black Pepper Extract
  • Boron
  • May suppress estrogen levels by preventing its conversion from testosterone
  • High dose of ashwagandha may cause sleepiness or increase the effects of sedatives.
  • D-Aspartic does not increase testosterone
  • Individual ingredient does not have sufficient evidence
  • Overall formulation is not clinically tested
  • Cause diarreha

Which natural testosterone supplement works best?

According to functional health expert AJ Brookes, Tongkat Ali is on top of the list among clinically proven natural supplements that increase free and total testosterone.

He said “There are sufficient human clinical studies on Tongkat Ali’s effect on testosterone and it works best with Vitamin D, zinc, Vitamin B to complement your existing health stack”.

Which is the best testosterone supplement brand?

Natural bodybuilding association Your Natural Federation (YNF) co-founder Andric Liew said that AKARALI is one of the best natural testosterone supplements for serious sport amateurs, bodybuilders and fitness health coaches.

AKARALI is regarded as the best natural testosterone booster used by natural bodybuilders in Australia, UK and US due to its clinically tested Tongkat Ali hot water root extract technology.

“Drugs-free bodybuilders and men over 40 trust AKARALI Tongkat Ali compared to Solaray Tongkat Ali or Doublewood Tongkat Ali due to its high potency and efficacy”,  said Andric, co-founder of YNF Australia. 

YNF promotes Tongkat Ali as a safe natural testosterone booster to its members, natural bodybuilders and other fitness communities in Australia.

Are Testosterone Supplements Safe?

Testosterone boosters containing Fadogia Agrestis cause liver and kidney damage based on a recent study in July 2023. Users are cautioned against taking Fadogia as it causes the death of liver tissue cells and chronic inflammation of kidneys at low dosages.

A case study on a person consuming multi-ingredient testosterone supplements showed high levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST), indicating liver injury – as shown in the ultrasound scan images below.

Abdominal ultrasound images of liver, spleen, kidneys, aorta, pancreas, gallbladder, , prostate and urinary bladder after taking multi-ingredient testosterone supplements (Source: Effect of testosterone boosters on body functions, 2018)

Does natural testosterone supplement work?

Yes, single-ingredient Tongkat Ali supplements are clinically tested to work to increase total and free testosterone in aging adults and moderately active men. Multiple studies and clinical trials showed a significant increase in total testosterone and free testosterone in men between 20-70 years old.

According to Head Scientist Dr Annie George from Biotropics, 200 mg of hot water Tongkat Ali extract may boost testosterone between 20% to 581% after 12 weeks based on a randomized clinical study when paired with multivitamins, zinc or magnesium.

The latest high-tech potent Tongkat Ali Physta® extract uses standardized hot water extraction technology that delivers 10x more testosterone boost than conventional ethanol-based 200:1 extract, making it the best natural testosterone supplement that is safe and effective.

According to US natural wellness expert Ilan Joffee, Malaysian Tongkat Ali root extract remains the best natural testosterone booster on Amazon for men in recent years.

He added, “Compared to Ginseng, Fadogia Agrestis or even Turkesterone, Tongkat Ali performs better due to substantial and consistent testosterone gains.”

Tongkat Ali is the best testosterone supplement due to its proven clinical tests on humans, backed by 20 years of research on testosterone, DHEA and DHT.

Is Tongkat Ali the best natural testosterone supplement?

Tongkat Ali has sufficient clinical evidence over the last 20 years to prove its effect on boosting testosterone, free-testosterone and DHEA in both men and women.

However, those exceptional testosterone gains will only work if you consume 100% Tongkat Ali root or clinically tested Tongkat Ali products due to quality standardization method during production.

Does Ashwagandha boost testosterone?

Yes, Ashwagandha increases total testosterone between 20% to 50% with lower gains compared to Tongkat Ali’s testosterone gains of between 50% to 600% when paired with multivitamins and other supplement stacks.

Which type of Tongkat Ali deliver the highest testosterone boost?

Testosterone supplements with Tongkat Ali hot water extract may deliver the highest testosterone gains up to 600% increase in total testosterone after 12 weeks based on a randomized clinical study. Potent Tongkat Ali hot water extract may work better to achieve higher testosterone gains. 

Does testosterone supplement affects kidneys or liver?

There are a few reported patient cases of kidney damage from users taking testosterone supplements containing Maca, Horny Goat Weed, Fadogia Agrestis. A July 2023 study showed adverse effects of liver and kidney damage caused by the daily consumption of Fadogia Agrestis at 50 mg/kg body weight after 14 days.

Testosterone supplements containing Fadogia Agrestis may not be safe for short-term consumption even at low dosages as it cause death of liver tissues (necrosis) and chronic kidney inflammation.

Which is the safest testosterone supplement?

Tongkat Ali may be one of the safest testosterone supplements on the market today with a high toxicity limit of 2,000 mg/kg body weight; a Human Equivalent Dose (HED) of 24,000 mg of Tongkat Ali based on a 75 kg adult.

In addition, Tongkat Ali is clinically tested to be safe for long-term consumption without any negative effects on the kidneys or liver based on the recommended dosage.

Parting Thoughts

Tongkat Ali, Panax Ginseng and Ashwagandha remained the popular T-booster supplements for men due to their decades of scientifically proven effects on libido and sperm motility, muscle strength, anaerobic performance in sports and mood.

You may want to take a single-ingredient natural supplement (eg: 100% Tongkat Ali extract) for a sustainable and healthy testosterone boost rather than taking a cocktail of a supplement stack.

Clinically tested testosterone supplements for men such as AKARALI continue to be the best testosterone supplement on Amazon and are used by serious sports amateurs and natural bodybuilders.

And you should seriously give it a try!

Naressa Khan contributes regularly on AKARALI. As a researcher and investigative journalist specializing in nutrition and natural wellness, Naressa is all about creating, deconstructing, and reassembling meaningful content through words and facts. With this approach always in mind, she eagerly explores the nuances in life via the aspects of lifestyle, culture, travel, health, and wellness in Malaysia .


The content published on this website is for educational purposes and should not be viewed, read, or seen as a prescription or constitute any form of medical advice. We recommend you consult your nearest GP or doctors before consuming Tongkat Ali or any products which contain Tongkat Ali. For further information, kindly refer to our Frequently Asked Questions (FAQ) for more information.

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7 Responses

  1. Great article! Excellent review about natural testosterone boosters. In my experience, the best testosterone supplement that I tried was the one containing Ginseng and Tongkat Ali. I understand you cannot combine those two herbs. But I tried two separate natural supplements within a span of 3 months. The Tongkat Ali performed way better after my blood test. The results showed increase of free testosterone after four solid weeks. I cannot remember the brand but it has standardized Tongkat Ali extract with 3% eurycomanone. I believe the amazing results were also attributed by my regular cardio. Well just maybe.

    1. Hi Jonathan, thanks for your comments. Yes, most consumers prefer using Tongkat Ali in various doses (between 100mg – 600mg) to restore, or to increase their testosterone levels. Most are men between 40-70 years. But please ensure you get the super-potent Tongkat Ali extract that is guaranteed to be the natural testosterone supplement that you ever need. The result from studies showed that testosterone levels can be boosted by 600% if you are taking multivitamins at the same time.

  2. How did TestoPrime can as one of the best testosterone booster? The product is crap and did not show any results. My testosterone was lower after consuming TestoPrime! Please avoid TestoPrime at all cost. It is not worth your money. Besides, the ingredients are formulated by a bunch of herbal junkies without any knowledge what it does to your health, kidney or other possible organ failure. We should educate people not to buy untested testosterone supplements and those fake T-boosters in the US. Spread the word!! Don’t spread hate. Spread love!

    1. Thanks for sharing your experience on various testosterone supplements. Not all T-boosters will work, and some are dangerous to health. We advice others to consult their respective doctors before consuming any testosterone supplements, T-boosters or even natural testosterone which are not clinically tested.

  3. The best testosterone supplement for men is Tongkat Ali. Period.

    Nothing beats this herb to be honest! I don’t understand why people think Fadogia Agrestis can do a better job in boosting testosterone. Are they blinded by whatever was said by Dr. Andrew Huberman on Joe Rogan’s podcast? Like seriously?? That dude is not even a scientist or expert in herbal formulation, research or even herbal extraction technologies!

    1. In our opinion, Fadogia Agrestis has less than 10 research studies in the last 30 years compared to Tongkat Ali (300+ research studies and clinical trials). But Fadgoia was heavily marketed with false claims by so-called experts in the USA. Fadogia has not reported effects on testosterone. There are very few T-booster supplements that are using Fadogia as one of the key active ingredients. The best testosterone supplements for men has Tongkat Ali or Panax Ginseng as their core active ingredients. Please avoid T-boosters which has Fadogia Agrestis in it, as it may not be tested against safety.

  4. It is interesting, or should i say I am thoroughly amused when reading the comments on this article. I can assure you one thing, the T-booster supplements in the US is just filled with junk products. So many health claims, but with so little results.

    WARNING TO READERS – Natural testosterone supplements can work positively for you if you find the right brand, or the right mix of ingredients. I tend to stick to single-ingredient supplement as my testosterone booster. Herbs like Tongkat Ali worked surprisingly well for my age (Iam 55). I will not argue about percentage increase of testosterone from my blood test, but the testosterone effects on my sexual desire, performance, erection and even general stamina is something to be proud of!

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